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Saturday, July 23, 2011
Tuesday, February 15, 2011
Saturday, July 03, 2010
Saturday, May 16, 2009
Saturday, May 09, 2009
Tuesday, April 28, 2009
Davidson's Internal Medicine 20th edition
Sunday, September 14, 2008
KAPLAN MEDICAL STEP 2 CS COURSE GUIDE
5-day course
GET IT HERE (USE WINRAR PROGRAM TO COMBINE ALL PARTS)
http://www.mediafire.com/?hphmhd50ugm (PART 1)
http://www.mediafire.com/?ync49ty09ca (PART 2)
http://www.mediafire.com/?mbx0o1xqrwm (PART 3)
http://www.mediafire.com/?yj1xmgdbgcb (PART 4)
GET IT HERE (USE WINRAR PROGRAM TO COMBINE ALL PARTS)
http://www.mediafire.com/?hphmhd50ugm (PART 1)
http://www.mediafire.com/?ync49ty09ca (PART 2)
http://www.mediafire.com/?mbx0o1xqrwm (PART 3)
http://www.mediafire.com/?yj1xmgdbgcb (PART 4)
Saturday, August 30, 2008
اللهم أنت ربي
Thursday, May 29, 2008
Saturday, May 03, 2008
Saturday, April 26, 2008
Salicylate overdose

The mixed respiratory alkalosis and metabolic acidosis in a sweaty, confused patient point towards salicylate overdose. The development of pulmonary oedema suggests severe poisoning and is an indication for haemodialysis
Salicylate overdose leads to a mixed respiratory alkalosis and metabolic acidosis. Early stimulation of the respiratory center leads to a respiratory alkalosis whilst later the direct acid effects of salicylates (combined with acute renal failure) may lead to an acidosis. In children metabolic acidosis tends to predominate
Features
- hyperventilation (centrally stimulates respiration)
- tinnitus
- lethargy
- sweating, pyrexia*
- nausea/vomiting
- hyperglycaemia and hypoglycaemia
- seizures
- coma
Treatment
- general (ABC, charcoal)
- urinary alkalinization is now rarely used - it is contraindicated in cerebral and pulmonary oedema with most units now proceeding straight to haemodialysis in cases of severe poisoning
- haemodialysis
Indications for haemodialysis in salicylate overdose
- serum concentration > 700mg/L
- metabolic acidosis resistant to treatment
- acute renal failure
- pulmonary oedema
- seizures
- coma
** Salicylates cause the uncoupling of oxidative phosphorylation leading to decreased adenosine triphosphate production, increased oxygen consumption and increased carbon dioxide and heat production
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